Microfluidics and Nanotechnology

1 Toward Unsupervised Smart Chemical Sensor Arrays

Tomazeli Duarte Leonardo and Jutten Christian

CONTENTS

1.1 Introduction

1.2 Smart Chemical Sensor Arrays

1.2.1 Potentiometric Sensors

1.2.2 Selectivity Issues in Potentiometric Sensors

1.2.3 Chemical Sensor Arrays

1.3 Blind Source Separation

1.3.1 Problem Description

1.3.2 Strategies to Perform BSS

1.3.2.1 ICA Methods

1.3.2.2 Bayesian Approach

1.3.3 Nonlinear Mixtures

1.4 Application of BBS Methods to Chemical Sensor Arrays

1.4.1 First Results

1.4.2 ICA-Based Methods for the Case with Different Valences

1.4.3 Use of Prior Information to Estimate the Electrode’s Slope

1.4.4 Bayesian Source Separation Applied to Chemical Sensor Arrays

1.5 Practical Issues

1.5.1 Dealing with the Scale Ambiguity ...