Installing Programs on 64-bit Versions of Windows
If you’re running an x64 version of Windows, you’ll notice the following differences when it comes to program installation:
16-bit Windows applications will not install.
64-bit programs will be installed, by default, in subfolders of the Program Files folder (%ProgramFiles%), but 32-bit programs will land in subfolders of a separate program-file folder called Program Files (x86).
While most programs designed for a 32-bit environment will run with full functionality in the x64 version of Windows, some might not, and certain of those might be courteous enough to notify you in advance:
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