4.2 Meta Design Setting

4.2.1 Notation

We consider k randomized trials where each trial has two treatment arms denoted by control and experimental and k greater than or equal to 1. The control arm may be a placebo or an active control, and the experimental arm may be an investigational drug in the clinical trial setting. However, in the medical device application, the control arm may be an old generation medical device and the experimental arm may refer to a new generation medical device. For ease of presentation, we generically call these two arms as control and experimental. ...

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