Microfluidics and Nanotechnology

3 Label-Free DNA Sensor Based on a Surface Long-Period Grating

Young-Geun Han

Biosensors have been attracting much attention in a variety of applications for bio-marker detection in medical diagnostics and pathogen or toxin detection in food and water. Conventional biosensors based on the fluoroimmunoassay technique should exploit the fluorescence labeling of the antigen or target DNA and always require additional reagents [1]. Ordinary biosensors have many disadvantages, such as high cost, a complicated configuration, and the impossibility of real-time detection. To overcome these drawbacks, many methods have been proposed for developing label-free detection biosensors [2,3]. In particular, fiber-optic biosensors are promising devices for high-quality, ...