Contents
- Preface to the second edition
- Abbreviations
- Notation
- IUnderstanding and performing Mendelian randomization Understanding and performing Mendelian randomization
- 1Introduction and motivation
- 1.1Shortcomings of classical epidemiology
- 1.2The rise of genetic epidemiology
- 1.3Motivating example: The inflammation hypothesis
- 1.4Other examples of Mendelian randomization
- 1.5Overview of book
- 1.6Summary
- 2What is Mendelian randomization?
- 2.1What is Mendelian randomization?
- 2.2Why use Mendelian randomization?
- 2.3A brief overview of genetics
- 2.4Classification of Mendelian randomization investigations
- 2.5Summary
- 3Assumptions for causal inference
- 3.1Observational and causal relationships
- 3.2Finding a valid instrumental variable
- 3.3Testing for a ...
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