Chapter 1Variations on a Theme of Control

Learning Objectives

  • Become familiar with the negative autoregulatory transcription circuit
  • Understand the importance of learning different mathematical methods
  • Explore common experimental techniques used in systems biology

Variations

When I was a young piano player, my teacher gave me a new piece to learn that I found fascinating. It was Mozart’s variations on a tune that I knew as “Twinkle, Twinkle, Little Star.” The piece begins with a simple rendition of the tune and then catapults into a fast series of scales, followed by 11 other variations, including key changes, dramatic shifts in tempo, and plenty else to keep my fingers busy.

What amazed me about this piece was how much I was able to learn ...

Get Fundamentals of Systems Biology now with the O’Reilly learning platform.

O’Reilly members experience books, live events, courses curated by job role, and more from O’Reilly and nearly 200 top publishers.