7

DSC applications: macromolecules

M.H. Chiu, N.S. Berezowski and E.J. Prenner,     University of Calgary, Alberta, Canada

Abstract:

DSC is a straightforward, non-perturbing thermodynamic technique first developed in the early 1960s. The large number of parameters and the high sensitivity has made DSC one of the key calorimetric tools used for investigating thermodynamic properties of biopolymers, proteins, peptides and nucleic acids. There are numerous reviews covering the different macromolecular applications of DSC: this chapter will primarily focus on proteins and nucleic acids.

Key words

DSC

proteins

nucleic acids

gene material

polysaccharides

biopolymers

dendrimers

conformational

studies

7.1 Introduction

Differential scanning calorimetry ...

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