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A very serious game that can cure the orphan diseases

In the inspiring tradition of Foldit, the game for determining protein shapes, Fit2Cure crowdsources the problem of finding drugs that can cure the many under-researched diseases of developing countries. Fit2Cure appeals to the player’s visual–even physical–sense of the world, and …

Data sharing drives diagnoses and cures, if we can get there (part 2)

Editor’s note: Earlier this week, Part 1 of this article described Sage Bionetworks, a recent Congress they held, and their way of promoting data sharing through a challenge. Data sharing is not an unfamiliar practice in genetics. Plenty of cell …

Data sharing drives diagnoses and cures, if we can get there (part 1)

The glowing reports we read of biotech advances almost cause one’s brain to ache. They leave us thinking that medical researchers must command the latest in all technological tools. But the engines of genetic and pharmaceutical innovation are stuttering for …

Discovering genetic associations using large data

David Heckerman from Microsoft Research presents a summary of his work in the session “Discovering Genetic Associations on Large Data.” This was part of the Strata Rx Online Conference: Personalized Medicine, a preview of O’Reilly’s conference Strata Rx, highlighting the …

Health records support genetics research at Children's Hospital of Philadelphia

Michael Italia from Children's Hospital of Philadelphia discusses the tools and methods his team uses to manage health care data.

Health records support genetics research at Children's Hospital of Philadelphia

Michael Italia from Children's Hospital of Philadelphia discusses the tools and methods his team uses to manage health care data.

Recombinant Research: Breaking open rewards and incentives

To move from a hothouse environment of experimentation to the mainstream of one of the world's most lucrative and tradition-bound industries, Sage Bionetworks must aim for its nucleus: rewards and incentives. Comparisons to open source software and a summary of tasks for Sage Congress.

Recombinant Research: Breaking open rewards and incentives

To move from a hothouse environment of experimentation to the mainstream of one of the world's most lucrative and tradition-bound industries, Sage Bionetworks must aim for its nucleus: rewards and incentives. Comparisons to open source software and a summary of tasks for Sage Congress.

Recombinant Research: Sage Congress plans for patient engagement

The Vioxx problem is just one instance of the wider malaise afflicting the drug industry. Managers from major pharma companies expressed confidence that they could expand public or "pre-competitive" research in the direction Sage Congress proposed. The sector left to engage is the one that's central to all this work--the public.

Recombinant Research: Sage Congress plans for patient engagement

The Vioxx problem is just one instance of the wider malaise afflicting the drug industry. Managers from major pharma companies expressed confidence that they could expand public or "pre-competitive" research in the direction Sage Congress proposed. The sector left to engage is the one that's central to all this work--the public.

Recombinant Research: Sage Congress promotes data sharing in genetics

Through two days of demos, keynotes, panels, and breakout sessions, Sage Congress brought its vision to a high-level cohort of 230 attendees from universities, pharmaceutical companies, government health agencies, and others who can make change in the field.

Recombinant Research: Sage Congress promotes data sharing in genetics

Through two days of demos, keynotes, panels, and breakout sessions, Sage Congress brought its vision to a high-level cohort of 230 attendees from universities, pharmaceutical companies, government health agencies, and others who can make change in the field.

Sage Congress: The synthesis of open source with genetics

A conversation with Sage Bionetworks founder Stephen Friend about how open source can support a business model in drug development, the progress of current data sharing projects, and more.

Collaborative genetics, part 5: Next steps for genetic commons

The final installment of this series, about a Sage Commons Congress on the open-source sharing of genetic research, looks at what Sage Bionetworks and its friends need to do.

Collaborative genetics, part 4: Private practice, how to respect the patient

The fourth installment of this series, about a Sage Commons Congress on the open-source sharing of genetic research, focuses in on the rights of patients and how they want researchers to treat their data.

Collaborative genetics, part 3: Dividing the pie, from research to patents

The third installment of this series, about a Sage Commons Congress on the open-source sharing of genetic research, explores the barriers that keep private companies and researchers from sharing their work.

Collaborative genetics, part 2: Five Easy Pieces, Sage's Federation

The second installment of this series, about a Sage Commons Congress on the open-source sharing of genetic research, looks at the reasons collaborative research is critical to finding new treatments.

Collaborative genetics, Part 1: The ambitious goals of Sage Commons Congress

The opening installment of this series, about a Sage Commons Congress on the open-source sharing of genetic research, explains the elements of modern research and how collaboration facilitates progress.

Personal Genome Project Expanding the Personal Gene Pool from 10 to 100,000

The Personal Gemone Project is evolving from a small pilot of ten to a massive collection of 100,000 public medical histories and DNA sequences. Find out how you can register to participate in an experiment that will lay the necessary foundation for a complete understanding of how one's genetic sequence affects health and disease.